RNA sequencing

Ergebnisse in 1 - 3 Wochen
Sofortiger Versand der Unterlagen
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RNA sequencing extends the understanding of tumor biology beyond the genome and shows which genes are actually active and represent therapeutic targets. It is a valuable complement to DNA sequencing and enables even more precise personalization of cancer therapy - ideal for patients who do not benefit from standard treatment or for whom special molecular markers need to be discovered.

Gene expression : Analysis of the expression of genes identified as mutated or relevant by DNA sequencing. This shows which genes are actually actively expressed in the tumor and are important for tumor biology.
Fusion gene identification : Detection of fusion events that are not always fully detected by DNA-based testing. Fusion genes are often therapeutically responsive and offer additional treatment options.
Alternative splicing variants : Detection of variants caused by alternative splicing that can lead to functional changes in proteins, particularly in genes such as SF3B1 .
Advanced immune profiling : Analysis of gene expression of immune checkpoint proteins (e.g. PD-L1, CTLA-4, LAG-3 ) and the immune environment (e.g. T cell infiltration) to evaluate suitability for immunotherapies and to find additional therapeutic approaches.

Areas of application:

Therapy resistance and relapses : For tumors that have become resistant after initial treatment or develop recurrent metastases.
Unclear mutation significance : Identified mutations whose functional significance is unclear.
Rare cancers : For tumors for which there are no clear molecular markers or to discover new therapeutic targets.
Heterogeneous tumors : In cancers with high tumor heterogeneity, to identify subpopulations and different gene activities.
Expanded immunotherapy options : To identify additional potential targets for immunotherapies beyond PD-L1 expression.

Advantages of RNA sequencing:

Supplementary information : Provides additional, functional insights into gene activity in the tumor that are not captured by DNA analysis alone.
Personalized therapy : Enables more precise decisions for targeted therapies, immunotherapies or combined treatment strategies.
Flexibility : Can be used for different types of cancer and is particularly valuable for difficult, therapy-resistant or rare tumors.

Procedure

Immediately after ordering, you will receive detailed instructions from us by email and a few days later by post, so that you can discuss them with your doctor or treating hospital. We are happy to support you with this. Feel safe and supported every step of the way!

If enough cancer cells have already been taken, the analysis can begin immediately. If additional samples are required, your doctor will discuss this with you. This will create the best conditions for an accurate analysis!

Our medical scientists and experienced pathologists precisely analyze and test your cancer cells. Depending on the package, you will receive the well-founded and decisive results for targeted cancer therapy within 1 to 3 weeks!

We have no influence on companies with whom we do not have a partnership. Therefore, we cannot influence the cost of additional cancer cell sampling, nor the speed, expertise or implementation of these measures. For this reason, we rely on your active cooperation or the support of a close person to ensure that the processes at your doctor's office run smoothly until the samples are collected.

Money-back guarantee

Your satisfaction and well-being are our top priority. If it is not possible to carry out a tissue sample for medical or organizational reasons, or if you find that you need a different package, we offer you a money-back guarantee and the option to change your package easily.

Conditions for refund:

Full reimbursement will be made if tissue sampling cannot be performed for medical reasons.
If the collection is not possible for organizational reasons on our part, you will also receive a full refund.
The refund applies to all costs directly related to the tissue collection and related services in the selected package.

Package change option:

If, after booking, you find that another package is a better fit for your diagnosis or situation – for example, if you have a very similar type of cancer – you can easily change your chosen package.
The difference will either be refunded or paid later, depending on the price difference between the packages.
A package change can be made at any time before the start of tests or treatments.

Refund and package change process:

If you would like a refund or package exchange, please contact our customer service team.
After reviewing your request, the refund or exchange will be processed within 14 working days.
The refund will be made using the same payment method you used for the original payment. If you change packages, the new price will be adjusted accordingly.

We want to make sure that you get exactly the services you need. That's why we offer you complete flexibility and security when choosing our packages. Your health and satisfaction are our top priority.

Medical note

If the progression of the cancer and urgent medical advice indicate that immediate treatment is necessary, we recommend that you start therapy. Once our results are available, treatment can be adjusted accordingly.

Maximum expansion

In addition to this package of genetic analyses and in vitro tests for approved drugs, we can also analyze other genes or test additional drugs that are of interest for the specific case, upon agreement.

Advanced genetic analyses:
Upon request and after consultation, we can specifically include additional genes or genetic markers in the analysis in order to obtain a more comprehensive molecular picture of the tumor. This enables even more precise adaptation of the treatment options to the individual genetic characteristics of the tumor.

Additional drug tests:
If there are specific cancer drugs of interest that are not part of this package, we can, by agreement, include additional drugs in the in vitro testing. This offers the opportunity to test alternative or complementary therapies that may be specifically relevant for the patient.

To use:

Maximum individualization of treatment through targeted expansion of genetic analysis.
Additional treatment options through testing of other approved medications.
Greater flexibility in adapting the treatment plan to complex or rare cancers.

Process:
If you would like additional analyses or drug tests, we will discuss the options with your treating physician. After a careful evaluation, we can integrate the desired genes or drugs into the testing process. This ensures that you receive the most comprehensive and precise information for the treatment decision.

Please contact us if you have any special requests or requirements. Together we will find the best solution to optimally support your treatment.

The offer is aimed at patients with particularly complex cases or rare cancers where additional genetic markers or alternative medications may be of interest.