FAQ - Questions and Answers

Why CancerGen Labs’ personalized diagnostics make the difference

Personalized cancer therapy offers far more precise and individually tailored treatment strategies than conventional standard procedures. We use the latest molecular analyses and in vitro tests to develop tailor-made treatment approaches that offer the best chance of success. Below we explain the entire process, from sample collection to therapy evaluation, and answer frequently asked questions. You will also find a glossary of important technical terms to help you better understand the medical background.

For easy understanding without medical expertise

General procedure

Why is this process better than the standard procedure?

The standard procedure often only chooses a general treatment approach based on the type and stage of cancer. Our personalized diagnostics, on the other hand, examine the specific genetic and molecular properties of your cancer cells. This allows us to identify therapies that are precisely tailored to your tumor. This reduces the likelihood that you will have to undergo ineffective or stressful treatments and increases your chances of a successful therapy.

Why your doctor does not perform molecular diagnostics and therapy evaluation

Precise molecular analysis of tumors and comprehensive therapy evaluation require specialized technologies and expert knowledge that go beyond what is available in a regular doctor's office or clinic. Here are some of the key reasons why CancerGen Labs undertakes these highly specialized tasks:

  1. State-of-the-art technology
    CancerGen Labs uses advanced laboratory equipment and technologies such as next-generation sequencing (NGS) and digital PCR that are specifically designed to analyze genetic and molecular changes in cancer cells at a deep level. These devices are very complex and require specialized expertise that is typically found in specialized laboratories such as ours, but not in a typical physician's office setting.
  2. Expertise in molecular oncology
    Our laboratory staff are experts in molecular oncology and genetics. They specialize in analyzing and interpreting the complex genetic profiles of tumors. This type of evaluation requires specific knowledge of cancer biology, molecular signaling pathways and the latest advances in personalized medicine. This expertise is often not available in a typical medical setting because it requires in-depth specialized knowledge.
  3. Broad-based in vitro therapy evaluation
    Our in vitro therapy evaluation tests how tumor cells respond to a variety of treatment options, including chemotherapy, radiation therapy, immunotherapy and targeted therapies. These tests require specialized laboratory techniques that allow cancer cells to be cultured and analyzed outside the body. This is typically not possible in a clinical practice or hospital setting because it requires specialized laboratory environments and techniques.
  4. Personalized analysis instead of standard procedures
    While your doctor is able to offer standard diagnoses and therapies, we focus on deciphering the molecular details of your tumor that are not analyzed in usual clinical practice. Through our precise molecular diagnostics, we can recommend targeted therapies based on the individual genetic changes in your cancer cells. This often leads to better outcomes because instead of applying "one treatment fits all," a customized therapy is developed.
  5. Collaboration with your doctor
    Your treating physician plays a central role in your care by using the results of our diagnostics and therapy evaluations to plan and carry out your treatment. We ensure that he or she receives the necessary information to make informed decisions. By having CancerGen Labs handle the highly specialized molecular diagnostics and therapy evaluation, we enable your physician to provide you with the most precise and effective treatment without having to deal with the technical challenges and burden of the laboratory analyses themselves.

Overall, we offer sophisticated diagnostics and tests that go far beyond the capabilities of a standard examination. Our collaboration with your doctor ensures that you benefit from the most advanced techniques and knowledge available, while your doctor can guide treatment according to tailored results.

How is the sample taken?

The sample will be taken by your doctor. This can be a tissue sample (biopsy) or a blood sample, depending on the type of tumor or leukemia you have. There is a possibility that enough material is already in stock and it can be sent in directly.

What happens after the sample is taken?

The sample will be carefully packaged and safely delivered to our laboratory by a specialized courier. There we will begin the analysis to examine the molecular and genetic properties of your cancer cells.

How long does it take to get the results?

It usually takes 10-21 days for the results of your molecular analysis and therapy evaluation to be completed. We will inform you and your doctor as soon as the report is available and discuss the results with you.

Does my doctor support the individual therapy approach?

Your doctor is responsible for the treatment and decides how the molecular diagnostics and therapy recommendations provided by CancerGen Labs are integrated into your treatment planning. Our analysis results provide a sound basis for developing a personalized treatment strategy together with your doctor that is tailored to the specific characteristics of your cancer.

However, if your doctor does not support this approach for personal reasons, we can provide you with a list of clinics and specialists in your area who have experience with personalized therapy approaches. This recommendation is made on a neutral basis and solely in the interest of providing you with the best possible care. Of course, the choice of clinic or doctor is entirely up to you. We pay strict attention to transparency and independence.

Does the health insurance company pay for advanced molecular diagnostics?

Whether the health insurance company covers the costs of molecular diagnostics depends on various factors:

  1. Guideline-compliant use : Molecular diagnostics are generally only covered by statutory health insurance if they are recommended in the guidelines for the treatment of certain types of cancer. They are often used for tumor types such as lung or breast cancer, especially when targeted therapy is planned.
  2. Demonstrable effect on the treatment decision : Costs are usually only covered if the molecular diagnostics have a significant influence on the choice of therapy. This means that the diagnosis serves to enable personalized treatment, e.g. through the use of targeted medication.
  3. Individual case review : In many cases, an individual case review by the health insurance company is required. The treating doctor must justify the need for the diagnosis and explain how it supports the treatment decision. It is therefore advisable to clarify the cost coverage with the health insurance company in advance.
  4. Private health insurance companies : Private health insurance companies are often more flexible and cover the costs of molecular diagnostics more often than statutory health insurance companies. However, the exact coverage depends on the individual contract conditions. Here, too, it is advisable to make an inquiry to the insurance company in advance.

In any case, you should discuss with your treating physician and your health insurance company whether and under what conditions the costs for molecular diagnostics will be covered.

Diagnostics

What exactly is examined in molecular diagnostics?

Our diagnostics go far beyond what is examined in conventional procedures. We analyze the DNA and RNA of your cancer cells for genetic mutations, changes in the tumor structure and molecular markers that are of key importance for the treatment decision. This detailed analysis allows us to identify the specific weaknesses of the tumor that can be targeted by certain therapies.

Why is this diagnostic better than conventional tests?

Conventional tests often only provide general information about the tumor type and its growth pattern. Our molecular diagnostics analyze in depth the biological mechanisms that drive the cancer. This allows us to propose targeted therapies that would not be suitable for every patient, but may work specifically for you. This enables personalized treatment that is tailored to your individual tumor.

What is a mutation and why is it important to consider it?

A mutation is a change in the genetic code of your cells. Some mutations can promote the growth of cancer cells, others make them susceptible to certain drugs. By identifying such mutations, we can recommend targeted therapies that are tailored to the genetic characteristics of your tumor cells, which usually leads to better treatment results.

Therapy evaluation

What is the difference between standard therapy and personalized therapy?

Standard therapy follows general treatment recommendations for specific types of cancer. Personalized therapy, on the other hand, takes into account the genetic and molecular background of your tumor. This means that you will receive therapy that is specifically tailored to the characteristics of your cancer cells, which significantly increases the likelihood of successful treatment.

How does therapy evaluation help in selecting the right treatment?

In vitro therapy evaluation involves testing how your tumor cells respond to different therapies, including chemotherapy, radiotherapy, immunotherapy and targeted drugs. This precise approach makes it possible to determine in advance which treatment is likely to be most effective for your tumor, while avoiding less effective or unnecessarily burdensome therapies.

Why is in vitro therapy evaluation better than a classic therapy decision?

Conventional therapies often rely on experience or general treatment protocols. Our in vitro evaluation tests your tumor cells directly for their response to different treatment options. This gives us a very accurate picture of which therapy works best and allows us to optimize therapy planning accordingly, leading to a higher success rate.